SCHEMBL9656292

SCHEMBL9656292

CC(C)=C1CC(=O)N(c2cc(OC(F)(F)F)c(Cl)cc2Cl)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
PKM P14618 2/20 0.38
KCNN4 O15554 2/20 0.34
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33
PGK1 P00558 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
P2RX7 Q99572 1/20 0.31
NOTUM Q6P988 2/20 0.31
MEN1 O00255 1/20 0.31
CASP6 P55212 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
CCR6 P51684 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655288 0.92 PPOX (0.40) KCNN4ALDH1A1PPOX
SCHEMBL9654778 0.84 PKM (0.46) GAAPKMMEN1CASP6KMT2A
SCHEMBL9656299 0.83 NOTUM (0.44) GAAKCNN4NOTUMMEN1KMT2A
SCHEMBL9655971 0.82 GAA (0.38) GAAPKMHCRTR1HCRTR2MEN1
SCHEMBL9654591 0.81 GAA (0.45) GAAPKMALDH1A1PPOX
SCHEMBL9655304 0.81 CYP2C9 (0.43) GAAPKMMEN1KMT2AALDH1A1
SCHEMBL9655637 0.81 PKM (0.41) GAAPKMALDH1A1HSP90AA1MAPT
SCHEMBL9654864 0.81 GAA (0.52) GAAPKMMEN1KMT2AALDH1A1
SCHEMBL9654784 0.79 PPOX (0.43) GAAPKMEGLN1PPOXRORC
SCHEMBL9652343 0.79 PPOX (0.50) GAAPKMALDH1A1MAPTPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed