SCHEMBL9656299

SCHEMBL9656299

CC(C)=C1CC(=O)N(c2ccc(Cl)c(OC(F)(F)F)c2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.44
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
PDE3A Q14432 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
IDH1 O75874 2/20 0.35
KCNN4 O15554 2/20 0.34
ENPP2 Q13822 1/20 0.34
GAA P10253 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9656318 0.85 ALDH1A1 (0.36) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9655555 0.85 LMNA (0.45) NOTUMALDH1A1MAPTKDM4ELMNA
SCHEMBL9653027 0.83 RXRA (0.38) ALDH1A1MAPTKDM4E
SCHEMBL9656292 0.83 GAA (0.38) NOTUMALDH1A1MAPTPDE3AMEN1
SCHEMBL9656317 0.82 RXRA (0.40) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9653017 0.82 ALDH1A1 (0.40) ALDH1A1MAPTKDM4ELMNAMEN1
SCHEMBL9655368 0.82 RORC (0.39) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9656338 0.82 ALDH1A1 (0.39) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9656399 0.80 KDM4E (0.37) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9656252 0.80 PDE4A (0.38) ALDH1A1MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed