Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11564981 | 0.98 | ALDH1A1 (0.47) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL11563269 | 0.83 | PTGS1 (0.56) | ALDH1A1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL9656015 | 0.82 | NPC1 (0.43) | HSD11B1ALDH1A1KDM4EHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL11565791 | 0.82 | PTGS1 (0.55) | ALDH1A1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL9654561 | 0.81 | PTGS1 (0.45) | HSD11B1ALDH1A1PTGS1NOTUMKDM4E | |
| SCHEMBL6678346 | 0.81 | ALDH1A1 (0.64) | HSD11B1ALDH1A1NOTUMKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL9656027 | 0.81 | NPC1 (0.42) | HSD11B1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL2442712 | 0.79 | HSD11B1 (0.54) | HSD11B1ALDH1A1NOTUMHPGDPSMB8 | |
| SCHEMBL11560255 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1PTGS1PTGS2KDM4E | |
| Hydrochloric Acid SCHEMBL11561831 | 0.78 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288185-B1 | THIADIAZOLE GUANIDINES | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1992-08-19 | — | — | EP | disclosed |