Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660007 | 0.90 | ABCB11 (0.50) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9657945 | 0.89 | ABCB11 (0.47) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9657963 | 0.86 | ABCB11 (0.55) | ABCB11ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9627379 | 0.85 | ABCB11 (0.68) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9660610 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL9656448 | 0.83 | ABCB11 (0.70) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9660000 | 0.81 | ABCB11 (0.44) | ABCB11ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9656392 | 0.81 | ABCB11 (0.49) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9629306 | 0.79 | ABCB11 (0.68) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9659152 | 0.79 | ABCB11 (0.52) | ABCB11ALDH1A1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |