Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656369 | 0.93 | L3MBTL1 (0.45) | LMNAMAPTKLK7KDM4EALDH1A1 | |
| SCHEMBL9657610 | 0.91 | LMNA (0.42) | LMNAMAPTKLK7KDM4EALDH1A1 | |
| SCHEMBL9657067 | 0.86 | CNR1 (0.43) | LMNAMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL9654974 | 0.86 | KDM4E (0.41) | LMNAKDM4EHTTALDH1A1ALOX5 | |
| SCHEMBL9657686 | 0.85 | HTT (0.40) | LMNAMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL9654896 | 0.84 | LMNA (0.45) | LMNAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9656725 | 0.84 | KMT2A (0.47) | HTTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9657784 | 0.83 | KMT2A (0.42) | LMNAMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL9654930 | 0.82 | L3MBTL1 (0.36) | LMNAMAPTKLK7KDM4EHTT | |
| SCHEMBL23271855 | 0.82 | HTT (0.58) | LMNAMAPTKLK7KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |