Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657610 | 0.95 | LMNA (0.42) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL9656394 | 0.93 | LMNA (0.40) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL9658382 | 0.86 | ELANE (0.47) | L3MBTL1KMT2ALMNASMN1; SMN2ELANE | |
| SCHEMBL9657137 | 0.85 | ELANE (0.46) | L3MBTL1LMNAHPGDSMN1; SMN2ELANE | |
| SCHEMBL9656624 | 0.85 | ELANE (0.46) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL9654727 | 0.85 | LTA4H (0.47) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL9654930 | 0.85 | L3MBTL1 (0.36) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL23271994 | 0.83 | ELANE (0.48) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL23271745 | 0.83 | HTT (0.56) | L3MBTL1KMT2ALMNAHPGDKLK7 | |
| SCHEMBL9660321 | 0.83 | SLC2A1 (0.46) | L3MBTL1KMT2ALMNASMN1; SMN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |