Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656721 | 0.88 | KMT2A (0.44) | PTGER4CYP1A2MAPTALDH1A1KMT2A | |
| SCHEMBL9660468 | 0.84 | TSHR (0.42) | MAPTALDH1A1KMT2APPARGNCOA2 | |
| SCHEMBL9656999 | 0.83 | TSHR (0.41) | MAPTALDH1A1KMT2APPARGNCOA2 | |
| SCHEMBL9660550 | 0.83 | SLC2A1 (0.44) | PTGER4CYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL9656724 | 0.81 | KDM4E (0.51) | CYP1A2MAPTALDH1A1KMT2APPARG | |
| SCHEMBL5706171 | 0.81 | LTA4H (0.62) | CYP1A2CYP2D6LTA4HMAPTKMT2A | |
| SCHEMBL9658198 | 0.80 | ALDH1A1 (0.47) | PTGER4CYP1A2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL9641997 | 0.80 | KDM4E (0.51) | PTGER4CYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL9657082 | 0.80 | MAPT (0.44) | CYP1A2LTA4HMAPTALDH1A1KMT2A | |
| SCHEMBL9658456 | 0.79 | ALDH1A1 (0.45) | PTGER4CYP1A2CYP2D6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |