SCHEMBL9656782

SCHEMBL9656782

CO[PH](=O)N(C)C(=O)C(C)Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.54
LIPE Q05469 1/20 0.53
ALDH1A1 P00352 4/20 0.51
FFAR1 O14842 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
ATM Q13315 1/20 0.47
HTT P42858 2/20 0.46
RAB9A P51151 1/20 0.45
HPGD P15428 1/20 0.44
PPARG P37231 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Haloxyfop-P-Methyl SCHEMBL54547 0.82 LMNA (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1
Haloxyfop-P-Methyl SCHEMBL54814 0.82 LMNA (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1
Haloxyfop-P-Methyl SCHEMBL29514646 0.82 LMNA (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1
Haloxyfop-P-Methyl SCHEMBL29370417 0.82 LMNA (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1
SCHEMBL9656793 0.82 SMN1; SMN2 (0.51) LMNASMN1; SMN2LIPEALDH1A1FFAR1
SCHEMBL9363159 0.82 SMN1; SMN2 (0.61) LMNASMN1; SMN2LIPEALDH1A1FFAR1
SCHEMBL9449585 0.82 SMN1; SMN2 (0.61) LMNASMN1; SMN2LIPEALDH1A1FFAR1
Haloxyfop SCHEMBL33627 0.82 SMN1; SMN2 (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1
Haloxyfop-R-Methyl SCHEMBL119996 0.82 SMN1; SMN2 (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1
Haloxyfop SCHEMBL3675562 0.82 SMN1; SMN2 (0.65) LMNASMN1; SMN2LIPEALDH1A1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433446-B1 HERBICIDAL ORGANO-PHOSPHORUS COMPOUNDS TEIJIN LIMITED (JP) 1992-12-30 EP disclosed
EP-0433446-A1 HERBICIDAL ORGANO-PHOSPHORUS COMPOUNDS. TEIJIN LTD (JP) 1991-06-26 EP disclosed
WO-1989012057-A1 HERBICIDAL ORGANO-PHOSPHORUS COMPOUNDS TEIJIN LIMITED (JP) 1989-12-14 WO disclosed
US-4838923-A FOR NARROW-LEAVED WEEDS TEIJIN LIMITED (JP) 1989-06-13 US disclosed