SCHEMBL9656793

SCHEMBL9656793

CCO[PH](=O)N(CC)C(=O)C(C)Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.51
LMNA P02545 3/20 0.51
FFAR1 O14842 1/20 0.49
LIPE Q05469 1/20 0.48
ALDH1A1 P00352 4/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PPARG P37231 1/20 0.46
HTT P42858 1/20 0.43
ATM Q13315 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
XBP1 P17861 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9657396 0.85 FFAR1 (0.49) LMNAFFAR1KMT2AMEN1L3MBTL1
SCHEMBL9655066 0.84 LMNA (0.47) LMNALIPE
SCHEMBL9657438 0.83 MEN1 (0.37) KMT2AMEN1PPARG
SCHEMBL9656782 0.82 LMNA (0.56) SMN1; SMN2LMNAFFAR1LIPEALDH1A1
SCHEMBL731273 0.81 L3MBTL1 (0.62) SMN1; SMN2LMNAFFAR1LIPEALDH1A1
SCHEMBL10844228 0.80 SMN1; SMN2 (0.56) SMN1; SMN2LMNAFFAR1LIPEALDH1A1
SCHEMBL10851492 0.79 SMN1; SMN2 (0.55) SMN1; SMN2LMNAFFAR1LIPEALDH1A1
Haloxyfop SCHEMBL3675562 0.79 SMN1; SMN2 (0.65) SMN1; SMN2LMNAFFAR1LIPEALDH1A1
SCHEMBL9363159 0.79 SMN1; SMN2 (0.61) SMN1; SMN2LMNAFFAR1LIPEALDH1A1
SCHEMBL9449585 0.79 SMN1; SMN2 (0.61) SMN1; SMN2LMNAFFAR1LIPEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433446-B1 HERBICIDAL ORGANO-PHOSPHORUS COMPOUNDS TEIJIN LIMITED (JP) 1992-12-30 EP disclosed
EP-0433446-A1 HERBICIDAL ORGANO-PHOSPHORUS COMPOUNDS. TEIJIN LTD (JP) 1991-06-26 EP disclosed
WO-1989012057-A1 HERBICIDAL ORGANO-PHOSPHORUS COMPOUNDS TEIJIN LIMITED (JP) 1989-12-14 WO disclosed
US-4838923-A FOR NARROW-LEAVED WEEDS TEIJIN LIMITED (JP) 1989-06-13 US disclosed