Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055593 | 0.78 | CYP3A4 (0.37) | SMN1; SMN2MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1451183 | 0.78 | KDM4E (0.41) | SMN1; SMN2KMT2ATDP1KDM4EHTT | |
| SCHEMBL1521695 | 0.78 | CYP2A6 (0.44) | KDM4EPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL715110 | 0.75 | PTGS2 (0.45) | CDC25BMEN1KMT2ATDP1HTT | |
| SCHEMBL467479 | 0.75 | GABRA1 (0.38) | PTPRCCTSLCTSSPTPN13LMNA | |
| SCHEMBL7772699 | 0.75 | CDC25B (0.46) | CDC25BSMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL29666462 | 0.75 | CDC25B (0.46) | CDC25BSMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL4808960 | 0.74 | TRIM24 (0.36) | CDC25BSMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL6716159 | 0.74 | RUNX1 (0.34) | SMN1; SMN2MEN1KMT2AKDM4ETP53 | |
| SCHEMBL2039645 | 0.74 | ALDH1A1 (0.33) | PTPRCCTSLCTSSPTPN13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128335-A | Antibiotics | MERCK & CO., INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0481662-A1 | 2-Heteroarylphenyl-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |