Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658627 | 0.87 | PTGS1 (0.56) | MRGPRX1PTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL9657535 | 0.87 | PTGS1 (0.60) | PTGS1PTGS2SMN1; SMN2HPGDMAPT | |
| SCHEMBL29748830 | 0.85 | PTGS2 (0.55) | PTGS2SMN1; SMN2MAPTCYP1A2CYP3A4 | |
| SCHEMBL441676 | 0.85 | PTGS2 (0.55) | PTGS2SMN1; SMN2MAPTCYP1A2CYP3A4 | |
| SCHEMBL9658252 | 0.84 | CXCL8 (0.48) | PTGS1PTGS2SMN1; SMN2HPGDMAPT | |
| SCHEMBL9655194 | 0.83 | SCN9A (0.48) | PTGS1PTGS2SMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL6599365 | 0.80 | PTGS2 (0.48) | MRGPRX1PTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL9658297 | 0.80 | ALDH1A1 (0.50) | MRGPRX1PTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL9656876 | 0.79 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2HPGDMAPT | |
| SCHEMBL9658654 | 0.79 | SMN1; SMN2 (0.45) | MRGPRX1PTGS1PTGS2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |