Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9656965 | 0.86 | PTGS2 (0.50) | PTGS2BRD4LMNAEP300MAPK14 | |
| SCHEMBL8107798 | 0.85 | PTGS2 (0.56) | PTGS2BRD4CYP19A1EPAS1 | |
| SCHEMBL9656894 | 0.84 | PTGS2 (0.58) | PTGS2BRD4CYP19A1EPAS1 | |
| SCHEMBL9658618 | 0.84 | PTGS2 (0.58) | PTGS2BRD4LMNAEP300CYP19A1 | |
| SCHEMBL8524487 | 0.83 | PTGS2 (0.59) | PTGS2BRD4EP300MAPK14EPAS1 | |
| SCHEMBL9656825 | 0.83 | PTGS2 (0.54) | PTGS2BRD4MAPK14 | |
| SCHEMBL9657391 | 0.82 | PTGS2 (0.51) | PTGS2BRD4EP300 | |
| SCHEMBL9655254 | 0.82 | PTGS2 (0.58) | PTGS2BRD4EP300 | |
| SCHEMBL9656909 | 0.82 | PTGS2 (0.56) | PTGS2BRD4EP300CYP19A1EPAS1 | |
| SCHEMBL9657522 | 0.82 | PTGS2 (0.56) | PTGS2BRD4EP300CYP19A1EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |