Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656662 | 0.91 | EPHX1 (0.53) | EPHX1FAAHRAB9AALDH1A1 | |
| SCHEMBL9658220 | 0.87 | EPHX1 (0.55) | EPHX1FAAHRAB9AALDH1A1HPGD | |
| SCHEMBL9656686 | 0.86 | RAB9A (0.56) | EPHX1FAAHRAB9AALDH1A1GAA | |
| SCHEMBL9656674 | 0.83 | ALDH1A1 (0.60) | EPHX1FAAHRAB9AALDH1A1 | |
| SCHEMBL9658347 | 0.80 | NCEH1 (0.48) | ALDH1A1GAAPOLBKMT2A | |
| SCHEMBL9658477 | 0.79 | KMT2A (0.43) | EPHX1FAAHRAB9AALDH1A1LMNA | |
| SCHEMBL9657148 | 0.79 | ALDH1A1 (0.53) | EPHX1FAAHRAB9AALDH1A1KMT2A | |
| SCHEMBL9656815 | 0.78 | SMN1; SMN2 (0.42) | ALDH1A1GAALMNAALOX12SMN1; SMN2 | |
| SCHEMBL9656632 | 0.77 | KMT2A (0.49) | FAAHRAB9AALDH1A1GAALMNA | |
| SCHEMBL9656605 | 0.77 | NCEH1 (0.44) | EPHX1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |