Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978037 | 0.85 | CYP19A1 (0.46) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL11018513 | 0.85 | ADRA2C (0.45) | LMNAPKMADRA2CHTTCYP19A1 | |
| Hydrochloric Acid SCHEMBL11251306 | 0.84 | ADRA2C (0.44) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL11161606 | 0.83 | ADRA2C (0.43) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL11158483 | 0.83 | ADRA2C (0.43) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL15927738 | 0.83 | ADRA2C (0.59) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL5971464 | 0.83 | ADRA2C (0.43) | LMNAPKMADRA2CHTTTP53 | |
| SCHEMBL10299485 | 0.83 | ADRA2C (0.59) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL8706510 | 0.83 | ADRA2C (0.43) | LMNAPKMADRA2CHTTCYP19A1 | |
| SCHEMBL12219350 | 0.82 | LMNA (0.42) | LMNAPKMADRA2CHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051439-A | Triazole derivatives of arylmethylaminoallylaryl compounds | HAFSLUND NYCOMED PHARMA AKTIENGESELLSCHAFT (AT) | 1991-09-24 | — | — | US | disclosed |
| US-4965277-A | Fungicides | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1990-10-23 | — | — | US | disclosed |
| EP-0351696-A2 | Allylaminoethylazoles | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1990-01-24 | — | — | EP | disclosed |