Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656962 | 0.88 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2HTTGFER | |
| SCHEMBL9656747 | 0.88 | KMT2A (0.42) | MEN1KMT2AL3MBTL1HTTGFER | |
| SCHEMBL9654914 | 0.86 | ABCB11 (0.59) | MEN1KMT2AL3MBTL1ABCB11SMN1; SMN2 | |
| SCHEMBL9657969 | 0.84 | MRGPRX4 (0.45) | MEN1KMT2ASMN1; SMN2HTTGFER | |
| SCHEMBL9658170 | 0.83 | ABCB11 (0.46) | MEN1KMT2AL3MBTL1ABCB11HTT | |
| SCHEMBL9659120 | 0.83 | SMN1; SMN2 (0.46) | MEN1KMT2AL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL9658201 | 0.82 | ABCB11 (0.45) | MEN1KMT2AABCB11SMN1; SMN2TUBB4A | |
| SCHEMBL9658516 | 0.81 | KMT2A (0.44) | MEN1KMT2AL3MBTL1ABCB11TUBB4A | |
| SCHEMBL9657625 | 0.79 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9656702 | 0.79 | ABCB11 (0.41) | MEN1KMT2AL3MBTL1ABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |