Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658516 | 0.93 | KMT2A (0.44) | ABCB11ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9656702 | 0.91 | ABCB11 (0.41) | ABCB11ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9657605 | 0.89 | ABCB11 (0.39) | ABCB11ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9654974 | 0.85 | KDM4E (0.41) | ALDH1A1POLBKDM4ELMNA | |
| SCHEMBL9654661 | 0.85 | ABCB11 (0.63) | ABCB11ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL9657088 | 0.82 | ABCB11 (0.39) | ABCB11ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9657653 | 0.82 | MEN1 (0.44) | ABCB11ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9659599 | 0.81 | KDM4E (0.42) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9659152 | 0.80 | ABCB11 (0.52) | ABCB11ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9656665 | 0.80 | ABCB11 (0.47) | ABCB11ALDH1A1HPGDTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |