Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657795 | 0.76 | TP53 (0.37) | TDP1ALDH1A1 | |
| SCHEMBL21306552 | 0.76 | CHRNB2 (0.50) | MAPK1TDP1ALDH1A1 | |
| SCHEMBL11277515 | 0.75 | USP2 (0.35) | TDP1ALDH1A1 | |
| SCHEMBL11287067 | 0.73 | TDP1 (0.34) | HPGDSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL9684043 | 0.73 | TP53 (0.34) | TDP1ALDH1A1MAPT | |
| SCHEMBL12908208 | 0.72 | MAPT (0.62) | MAPK1SMN1; SMN2TDP1SIGMAR1HDAC4 | |
| SCHEMBL928888 | 0.72 | MAPT (0.62) | MAPK1SMN1; SMN2TDP1SIGMAR1HDAC4 | |
| SCHEMBL14270533 | 0.72 | MAPT (0.62) | MAPK1SMN1; SMN2TDP1SIGMAR1HDAC4 | |
| SCHEMBL12908203 | 0.72 | MAPT (0.62) | MAPK1SMN1; SMN2TDP1SIGMAR1HDAC4 | |
| SCHEMBL10549828 | 0.72 | USP2 (0.33) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358459-A | Cyclopropane carboxylic acid and process for their production and use | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |