Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 3/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301269 | 0.85 | MTNR1A (0.63) | MTNR1AMTNR1BMEN1KMT2ACASR | |
| SCHEMBL9392741 | 0.85 | MTNR1A (0.58) | MTNR1AMTNR1BMEN1KMT2ACASR | |
| SCHEMBL9657323 | 0.82 | CYP19A1 (0.49) | MEN1KMT2AGRIN2BLMNAMAPT | |
| SCHEMBL4178423 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BCASRAOC3L3MBTL1 | |
| SCHEMBL17295959 | 0.76 | MTNR1A (0.58) | MTNR1AMTNR1BMEN1KMT2ACASR | |
| SCHEMBL28862317 | 0.75 | POLB (0.43) | MEN1KMT2AL3MBTL1LMNAHTT | |
| SCHEMBL8661020 | 0.75 | AOC3 (0.54) | MTNR1AMTNR1BCASRAOC3L3MBTL1 | |
| SCHEMBL6490320 | 0.74 | AOC3 (0.62) | MTNR1AMTNR1BAOC3L3MBTL1ROCK2 | |
| SCHEMBL11174933 | 0.74 | AOC3 (0.50) | MTNR1AMTNR1BCASRAOC3L3MBTL1 | |
| SCHEMBL27499005 | 0.73 | TAAR1 (0.56) | MTNR1AMTNR1BCASRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502031-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND A PHARMACEUTICAL COMPOSITION. | NOVO NORDISK AS (DK) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007389-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK A/S (DK) | 1991-05-30 | — | — | WO | disclosed |