SCHEMBL27499005

SCHEMBL27499005

COc1cccc(CC(CCO)c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.56
MTNR1A P48039 3/20 0.53
MTNR1B P49286 3/20 0.53
ALDH1A1 P00352 2/20 0.52
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
CASR P41180 2/20 0.48
CYSLTR2 Q9NS75 1/20 0.46
CYSLTR1 Q9Y271 1/20 0.46
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
MAOB P27338 1/20 0.45
SIGMAR1 Q99720 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9856490 0.83 CHRM2 (0.56) TAAR1MTNR1AMTNR1BALDH1A1SLC6A2
SCHEMBL9230011 0.83 TAAR1 (0.54) TAAR1MTNR1AMTNR1BALDH1A1CRHBP
SCHEMBL9857075 0.83 CALM1 (0.54) TAAR1MTNR1AMTNR1BALDH1A1SLC6A2
SCHEMBL27528330 0.80 TAAR1 (0.70) TAAR1SIGMAR1
SCHEMBL2097831 0.79 MTNR1A (0.50) TAAR1MTNR1AMTNR1BALDH1A1SLC6A2
SCHEMBL26152585 0.78 MTNR1A (0.61) TAAR1MTNR1AMTNR1BALDH1A1SLC6A2
SCHEMBL6301269 0.77 MTNR1A (0.63) MTNR1AMTNR1BALDH1A1CASRHTT
SCHEMBL19675529 0.77 TAAR1 (0.65) TAAR1MTNR1AMTNR1BSLC6A2SLC6A4
SCHEMBL11505504 0.77 TAAR1 (0.49) TAAR1MTNR1AMTNR1BALDH1A1SLC6A2
SCHEMBL9392741 0.77 MTNR1A (0.58) TAAR1MTNR1AMTNR1BALDH1A1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1310924-C Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2007-04-18 CN disclosed
CN-1246299-C Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2006-03-22 CN disclosed
CN-1616465-A Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2005-05-18 CN disclosed
CN-1182915-C Chiral copper complex catalyst composition and method for asymmetrical preparation ס�ѻ�ѧ��ҵ��ʽ���� 2005-01-05 CN disclosed
CN-1314209-A Chiral copper complex catalyst composition and method for asymmetrical preparation SUMITOMO CHEMICAL CO (JP) 2001-09-26 CN disclosed
CN-1313277-A Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2001-09-19 CN disclosed