Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656570 | 0.85 | SCN1A (0.39) | ALDH1A1RAB9AFABP7FABP5EPHX1 | |
| SCHEMBL10641025 | 0.83 | KDM4E (0.44) | ALDH1A1FABP7FABP5FAAHMGLL | |
| SCHEMBL1353554 | 0.82 | ALDH1A1 (0.54) | ALDH1A1RAB9AFABP7FABP5FAAH | |
| SCHEMBL1787764 | 0.80 | ALDH1A1 (0.51) | ALDH1A1RAB9AFABP7FABP5FAAH | |
| SCHEMBL9657648 | 0.80 | MAPT (0.42) | ALDH1A1FABP7FABP5EPHX1KDM4E | |
| SCHEMBL9658327 | 0.77 | TP53 (0.38) | ALDH1A1FABP7FABP5EPHX1KDM4E | |
| SCHEMBL1788981 | 0.77 | ALDH1A1 (0.47) | ALDH1A1RAB9AFABP7FABP5FAAH | |
| SCHEMBL9657082 | 0.77 | MAPT (0.44) | ALDH1A1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL9657915 | 0.77 | ALDH1A1 (0.69) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL17720727 | 0.74 | FAAH (0.49) | ALDH1A1RAB9AFABP7FABP5FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |