Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658327 | 0.90 | TP53 (0.38) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL9656815 | 0.85 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL10641025 | 0.85 | KDM4E (0.44) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9658306 | 0.80 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9657075 | 0.78 | TP53 (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL9656686 | 0.77 | RAB9A (0.56) | SMN1; SMN2ALDH1A1HPGDLMNAGAA | |
| SCHEMBL9657774 | 0.76 | ABCB11 (0.41) | MAPTSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9656506 | 0.75 | TUBB4A (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL9656404 | 0.74 | PTGER4 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL9641997 | 0.73 | KDM4E (0.51) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |