Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351817 | 0.83 | MAPK8 (0.47) | GAAALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL28711054 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1IDO1TAAR1MAPT | |
| SCHEMBL9660291 | 0.80 | ESR1 (0.52) | GAAALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL9177757 | 0.80 | ALDH1A1 (0.51) | GAAALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL9660039 | 0.80 | ALDH1A1 (0.58) | GAAALDH1A1IDO1TAAR1CYP3A4 | |
| SCHEMBL5252421 | 0.79 | IDO1 (0.66) | ALDH1A1IDO1ADRA1ATAAR1MEN1 | |
| Hydrochloric Acid SCHEMBL9660303 | 0.78 | ALDH1A1 (0.56) | GAAALDH1A1IDO1TAAR1CYP3A4 | |
| SCHEMBL30374775 | 0.78 | CA2 (0.57) | GAAALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL9660217 | 0.78 | CA2 (0.74) | GAAALDH1A1CYP3A4AOC3CA2 | |
| Hydrochloric Acid SCHEMBL27256353 | 0.78 | ALDH1A1 (0.56) | GAAALDH1A1IDO1TAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162359-A | ANTIHYPERLIPOPROTEINEMIC 5-BENZYL SUBSTITUTED-BENZIMIDAZOLINE-2-THION DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-11-10 | — | — | US | disclosed |
| EP-0474109-A1 | New 5-benzyl-substituted benzimidazolin-2-thion derivatives and process for their preparation | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-03-11 | — | — | EP | disclosed |