Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658234 | 0.82 | CREBBP (0.54) | BRD4SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL9658204 | 0.81 | CREBBP (0.46) | BRD4MAPTALDH1A1CREBBP | |
| SCHEMBL9658316 | 0.80 | HSPB1 (0.57) | MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9655142 | 0.78 | PTGS2 (0.55) | BRD4MAPTALDH1A1 | |
| SCHEMBL22859971 | 0.77 | MAOB (0.46) | BRD4MAPTALDH1A1LMNAHTT | |
| SCHEMBL20155430 | 0.75 | TRPA1 (0.45) | BRD4TRPA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9658659 | 0.74 | AR (0.47) | BRD4TRPA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31371422 | 0.74 | BRD4 (0.43) | BRD4TRPA1MAPTALDH1A1SCN8A | |
| SCHEMBL9656997 | 0.73 | BRD4 (0.47) | BRD4ALDH1A1 | |
| SCHEMBL9658610 | 0.73 | HSD17B2 (0.46) | SLC6A2SLC6A3MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |