Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661237 | 0.84 | HSD17B10 (1.00) | HSD17B10POLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL9661093 | 0.82 | L3MBTL1 (0.71) | HSD17B10POLBCDC25BL3MBTL1PKM | |
| SCHEMBL9660330 | 0.81 | HSD17B10 (0.77) | HSD17B10POLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL8628655 | 0.80 | POLB (0.65) | HSD17B10POLBL3MBTL1PKMEGFR | |
| SCHEMBL13869746 | 0.79 | EGFR (0.49) | HSD17B10POLBL3MBTL1PKMEGFR | |
| SCHEMBL9661138 | 0.79 | CDC25B (0.47) | HSD17B10POLBCDC25BL3MBTL1PKM | |
| SCHEMBL3820448 | 0.78 | ALDH1A1 (0.74) | POLBL3MBTL1ALDH1A1MAPK1RAB9A | |
| SCHEMBL10443880 | 0.77 | HSD17B10 (0.61) | HSD17B10POLBL3MBTL1PKMEGFR | |
| SCHEMBL9661198 | 0.77 | HSD17B10 (0.74) | HSD17B10POLBL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL3079300 | 0.76 | HSD17B10 (0.68) | HSD17B10POLBALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |