Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329411 | 0.87 | HCAR2 (0.37) | HCAR2ATMCYP2C9CYP2C19KDM4E | |
| SCHEMBL186349 | 0.76 | CDK2 (0.39) | HCAR2KDM4EALDH1A1 | |
| SCHEMBL2924939 | 0.76 | CDK2 (0.39) | HCAR2GRM5CYP2C9CYP2C19KDM4E | |
| SCHEMBL186538 | 0.76 | HCAR3 (0.36) | HCAR2ATMGRM5KDM4EALDH1A1 | |
| SCHEMBL4265537 | 0.74 | HCAR2 (0.39) | HCAR2ATMKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9413739 | 0.72 | LCK (0.40) | CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL3647432 | 0.72 | RAB9A (0.44) | GRM5CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL231933 | 0.72 | — | — | |
| SCHEMBL23292685 | 0.71 | IGF1R (0.50) | HCAR2IGF1RCYP2C19SRCALDH1A1 | |
| SCHEMBL30424650 | 0.71 | IGF1R (0.50) | HCAR2IGF1RCYP2C19SRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466042-A2 | Microbiological process for the oxidation of methyl groups | LONZA AG (CH) | 1992-01-15 | — | — | EP | claimed |
| EP-0466042-A2 | Microbiological process for the oxidation of methyl groups | LONZA AG (CH) | 1992-01-15 | — | — | EP | disclosed |