Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP16 | P51512 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660984 | 0.84 | CA1 (0.51) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9659641 | 0.80 | MMP2 (0.53) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9661649 | 0.77 | MMP2 (0.52) | HTTL3MBTL1TDP1SMN1; SMN2MMP2 | |
| SCHEMBL921473 | 0.76 | ESR1 (0.52) | HTTPKMMEN1KMT2A | |
| SCHEMBL4901587 | 0.74 | POLB (0.62) | ALDH1A1POLBGAAPKM | |
| SCHEMBL5157299 | 0.74 | POLB (0.62) | ALDH1A1POLBGAAPKM | |
| SCHEMBL29599097 | 0.74 | POLB (0.62) | ALDH1A1POLBGAAPKM | |
| SCHEMBL8491364 | 0.73 | PKM (0.60) | MMP2MMP8MMP12MMP13MMP14 | |
| SCHEMBL9661788 | 0.72 | HTT (0.50) | HTTL3MBTL1TDP1SMN1; SMN2MMP2 | |
| SCHEMBL5204151 | 0.72 | ALOX5 (0.43) | TDP1ALDH1A1POLBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466096-A1 | Derivatives of 4-hydroxyphenylsulfone | JUJO PAPER CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |