Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610867 | 0.91 | HSP90AB1 (0.36) | HSP90AB1CYP4F2CYP4A11TSHRALDH1A1 | |
| Carbon Monoxide SCHEMBL964064 | 0.88 | HSP90AB1 (0.34) | HSP90AB1CYP4F2CYP4A11 | |
| SCHEMBL28304209 | 0.83 | HSP90AB1 (0.38) | HSP90AB1CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL1057171 | 0.81 | TSHR (0.43) | TSHRALDH1A1HSD17B10MAPTHTT | |
| SCHEMBL11553575 | 0.79 | — | — | |
| SCHEMBL29288243 | 0.79 | — | — | |
| SCHEMBL13838043 | 0.78 | TSHR (0.47) | TSHRALDH1A1HSD17B10MAPTHTT | |
| SCHEMBL4312216 | 0.77 | — | — | |
| SCHEMBL9972656 | 0.76 | KMT2A (0.31) | LMNAKMT2A | |
| SCHEMBL25285182 | 0.74 | HDAC4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250152728-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-05-15 | — | — | US | disclosed |
| US-20230321267-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-11759526-B2 | Method and molecules | MEDIMMUNE, LLC (US) | 2023-09-19 | — | — | US | disclosed |
| EP-4223319-A2 | METHOD AND MOLECULES | MedImmune, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3630732-B1 | METHOD AND MOLECULES | MEDIMMUNE LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| CN-110650947-B | Methods and molecules | 免疫医疗有限责任公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20200206359-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-07-02 | — | — | US | disclosed |
| EP-3630732-A1 | METHOD AND MOLECULES | Medimmune, LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| CN-110650947-A | Methods and molecules | 免疫医疗有限责任公司 | 2020-01-03 | — | — | CN | disclosed |
| WO-2018218093-A1 | METHOD AND MOLECULES | MEDIMMUNE, LLC (US) | 2018-11-29 | — | — | WO | disclosed |
| US-20160145212-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-26 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| EP-1978952-A2 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | Hemocorm Limited (GB) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085806-A2 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007085806-A2 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250152728-A1 | Method And Molecules | PAICS, EPCAM, SQLE | HSP90AB1 2508/4885CYP4F2 259/4885CYP4A11 856/4885 |
| US-20160145212-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | HSP90AB1 1022/4885CYP4F2 1312/4885CYP4A11 2174/4885 |
| US-20200206359-A1 | Method And Molecules | PAICS, EPCAM, SQLE | HSP90AB1 2508/4885CYP4F2 259/4885CYP4A11 856/4885 |
| US-20230321267-A1 | Method And Molecules | PAICS, EPCAM, SQLE | HSP90AB1 2508/4885CYP4F2 259/4885CYP4A11 856/4885 |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | MB, TFRC, CYC1 | HSP90AB1 945/4885CYP4F2 695/4885CYP4A11 1893/4885 |
| US-11759526-B2 | Method and molecules | PAICS, EPCAM, SQLE | HSP90AB1 2508/4885CYP4F2 259/4885CYP4A11 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.