Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106576 | 0.85 | TBXA2R (0.75) | TBXA2RALDH1A1MAPTMEP1BLMNA | |
| SCHEMBL10447516 | 0.85 | TAAR1 (0.70) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL11119146 | 0.83 | TBXA2R (0.77) | TBXA2RALDH1A1MAPTTBXAS1MEP1B | |
| SCHEMBL10461554 | 0.83 | TBXA2R (0.76) | TBXA2RALDH1A1MAPTTBXAS1MEP1B | |
| SCHEMBL2413993 | 0.83 | HDAC6 (0.58) | TBXA2RALDH1A1MAPTTBXAS1MMP1 | |
| SCHEMBL11108980 | 0.82 | TBXA2R (0.75) | TBXA2RALDH1A1MAPTTBXAS1MEP1B | |
| SCHEMBL11104856 | 0.82 | ALDH1A1 (0.77) | TBXA2RALDH1A1MAPTTBXAS1MEP1B | |
| SCHEMBL12676127 | 0.82 | TBXA2R (0.75) | TBXA2RALDH1A1MAPTTBXAS1MEP1B | |
| Daltroban SCHEMBL309160 | 0.82 | TBXA2R (1.00) | TBXA2RALDH1A1MAPTTBXAS1MEP1B | |
| SCHEMBL9661410 | 0.81 | CYP19A1 (0.58) | TBXA2RALDH1A1MAPTTBXAS1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173500-A | Inhibiting thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1992-12-22 | — | — | US | claimed |
| JP-2108677-A | — | — | None | — | — | JP | disclosed |
| US-5173500-A | Inhibiting thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1992-12-22 | — | — | US | disclosed |
| US-5037990-A | Antagonist, antagonism, bronchodilator; antiischemic agents, treatment of cardiovascular disorder, kidney dialysis; and antiulcer agent | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |
| JP-H02108677-A | SULFONAMIDE CONTAINING TETRAZOLYL RADICAL AND REMEDY CONTAINING THE SAME FOR METABOLIC SYSTEM DISEASE | BOEHRINGER MANNHEIM GMBH | 1990-04-20 | — | — | JP | disclosed |