Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.70 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287345 | 0.91 | ALDH1A1 (0.72) | TAAR1PRMT1HSD17B10CYP19A1TDP1 | |
| SCHEMBL5185902 | 0.85 | ALDH1A1 (0.56) | TAAR1PRMT1HSD17B10CYP19A1TDP1 | |
| SCHEMBL12042482 | 0.85 | ALDH1A1 (0.74) | TAAR1PRMT1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL9660601 | 0.85 | TBXA2R (0.70) | TAAR1CYP19A1TDP1ALDH1A1MAPT | |
| SCHEMBL1954496 | 0.84 | CYP19A1 (0.80) | CYP19A1ALDH1A1POLBCA1CA2 | |
| SCHEMBL13073727 | 0.84 | ALDH1A1 (0.64) | TAAR1PRMT1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL412302 | 0.84 | ALDH1A1 (0.79) | TAAR1PRMT1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL13073499 | 0.83 | TAAR1 (1.00) | TAAR1PRMT1HSD17B10TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3517769 | 0.82 | ALDH1A1 (0.77) | TAAR1PRMT1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL2413993 | 0.81 | HDAC6 (0.58) | PRMT1TDP1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292269-A1 | BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS, INC. (CA) | 2010-11-18 | — | — | US | disclosed |
| EP-0356989-A2 | Sulfon amides with a tetrazolyl rest, process for their preparation an therapeutic agents | Roche Diagnostics GmbH (DE) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292269-A1 | BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC3, BIRC2 | TAAR1 2301/4885PRMT1 309/4885HSD17B10 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.