Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | MMP7 | P09237 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MMP10 | P09238 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916863 | 0.87 | HDAC6 (0.76) | HDAC6HDAC8HDAC3MMP1HDAC2 | |
| SCHEMBL2411710 | 0.84 | PRMT1 (0.68) | HDAC6HDAC8HDAC3HDAC2TBXA2R | |
| SCHEMBL9660601 | 0.83 | TBXA2R (0.70) | MMP1MMP7TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL2413447 | 0.82 | ALDH1A1 (0.52) | HDAC6HDAC8HDAC3MMP1TBXA2R | |
| SCHEMBL2410992 | 0.81 | HDAC6 (0.59) | HDAC6HDAC8HDAC3HDAC2TBXA2R | |
| SCHEMBL10447516 | 0.81 | TAAR1 (0.70) | ALDH1A1LMNAHTTSMN1; SMN2PRMT1 | |
| SCHEMBL5185902 | 0.79 | ALDH1A1 (0.56) | MMP1ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13623387 | 0.76 | FLT1 (0.64) | MMP1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL14880225 | 0.75 | CES2 (0.64) | HDAC6HDAC8HDAC3MMP1HDAC2 | |
| SCHEMBL10592411 | 0.75 | MMP1 (0.55) | HDAC6HDAC8HDAC3MMP1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |