Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18670053 | 0.86 | KDM4E (0.46) | CFTRMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL8618607 | 0.84 | KDM4E (0.44) | CFTRMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL38662583 | 0.82 | ALDH1A1 (0.46) | POLBHSD17B10KDM4ENPSR1L3MBTL1 | |
| SCHEMBL6848062 | 0.82 | KDM4E (0.46) | CFTRMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL18682159 | 0.78 | CA1 (0.43) | HSD17B10MAPTKDM4EL3MBTL1MRGPRX4 | |
| SCHEMBL4691963 | 0.77 | CA12 (0.50) | CFTRMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL28062575 | 0.75 | ALDH1A1 (0.42) | POLBHSD17B10MAPTKDM4EL3MBTL1 | |
| SCHEMBL5943406 | 0.74 | CA12 (0.64) | POLBCFTRMAPTKDM4EKMT2A | |
| SCHEMBL16647662 | 0.74 | MRGPRX4 (0.51) | CFTRMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL1998616 | 0.74 | CES2 (0.60) | CFTRMAPTKDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |