Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660783 | 1.00 | MEN1 (0.30) | MEN1NPC1CA12CA2POLB | |
| SCHEMBL9661616 | 0.85 | LMNA (0.37) | MEN1NPC1CA12CA2POLB | |
| SCHEMBL9661614 | 0.85 | LMNA (0.37) | MEN1NPC1CA12CA2POLB | |
| SCHEMBL9660169 | 0.80 | NPC1 (0.36) | MEN1NPC1CA12CA2POLB | |
| SCHEMBL9660166 | 0.80 | NPC1 (0.36) | MEN1NPC1CA12CA2POLB | |
| SCHEMBL9660462 | 0.74 | HPGD (0.39) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL9660457 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL9690033 | 0.73 | SMN1; SMN2 (0.39) | MEN1CA12CA2POLBRAB9A | |
| SCHEMBL9690036 | 0.73 | SMN1; SMN2 (0.39) | MEN1CA12CA2POLBRAB9A | |
| SCHEMBL9661588 | 0.72 | NPC1 (0.44) | MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |