Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690036 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9661616 | 0.84 | LMNA (0.37) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9661614 | 0.84 | LMNA (0.37) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9690129 | 0.83 | CA12 (0.43) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9690121 | 0.83 | CA12 (0.43) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL9660705 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2LMNAHTTALDH1A1POLB | |
| SCHEMBL9660700 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2LMNAHTTALDH1A1POLB | |
| SCHEMBL9660787 | 0.78 | KMT2A (0.36) | SMN1; SMN2MEN1KMT2ALMNAHTT | |
| SCHEMBL9660795 | 0.78 | KMT2A (0.36) | SMN1; SMN2MEN1KMT2ALMNAHTT | |
| SCHEMBL9690661 | 0.78 | MAPT (0.55) | SMN1; SMN2MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |