Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659033 | 0.82 | POLB (0.49) | POLBHSD17B10GAAALDH1A1TDP1 | |
| SCHEMBL9659012 | 0.79 | HSD17B10 (0.49) | POLBHSD17B10GAAALDH1A1TDP1 | |
| SCHEMBL9661198 | 0.76 | HSD17B10 (0.74) | POLBHSD17B10GAAALDH1A1TDP1 | |
| SCHEMBL8967935 | 0.76 | CTSK (0.37) | POLBHSD17B10GAAALDH1A1TDP1 | |
| SCHEMBL1953848 | 0.75 | GAA (0.58) | HSD17B10GAAALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL9660785 | 0.74 | HTT (0.42) | POLBHSD17B10GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9661104 | 0.74 | ALDH1A1 (0.52) | POLBHSD17B10GAAALDH1A1TDP1 | |
| SCHEMBL9661884 | 0.73 | CA1 (0.48) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL852553 | 0.72 | GAA (0.51) | GAASMN1; SMN2ABL1HTTMEN1 | |
| SCHEMBL19328690 | 0.72 | GAA (0.55) | GAAALDH1A1SMN1; SMN2CYP3A4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |