Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | PTPRG | P23470 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506194 | 0.83 | LIG1 (0.47) | MEN1KMT2ALIG1HSD17B10ALDH1A1 | |
| SCHEMBL6542305 | 0.79 | TDP1 (0.57) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11870549 | 0.79 | ALDH1A1 (0.47) | CTSKTDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL9660797 | 0.76 | POLB (0.44) | TDP1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL5439225 | 0.72 | NPSR1 (0.46) | TDP1KMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL7821197 | 0.69 | KMT2A (0.44) | MEN1KMT2ALIG1HSD17B10ALDH1A1 | |
| SCHEMBL14613543 | 0.68 | GRIN2D (0.36) | CTSKTDP1MEN1KMT2ALIG1 | |
| SCHEMBL6803138 | 0.68 | KMT2A (0.36) | CTSKMEN1KMT2AALDH1A1GAA | |
| SCHEMBL19982393 | 0.68 | ALDH1A1 (0.46) | MEN1KMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL11256483 | 0.68 | SOD1 (0.43) | CTSKMEN1KMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559108-A | ANTIBIOTICS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0699681-A1 | Cephalosporin derivatives | Bristol-Myers Company (US) | 1996-03-06 | — | — | EP | disclosed |