Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690026 | 0.82 | TSHR (0.38) | NPC1KMT2AALDH1A1CASP3RAB9A | |
| SCHEMBL9660750 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KIF11TSHRNPSR1 | |
| SCHEMBL9660922 | 0.77 | ADRA2A (0.38) | NPC1KMT2AALDH1A1CASP3RAB9A | |
| SCHEMBL9689465 | 0.77 | NOTUM (0.32) | NPC1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL9660409 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9660892 | 0.76 | ALDH1A1 (0.31) | ALDH1A1MAPTATM | |
| SCHEMBL9661541 | 0.75 | POLB (0.38) | NPC1KMT2AALDH1A1CASP3RAB9A | |
| SCHEMBL9661596 | 0.74 | SMN1; SMN2 (0.39) | NPC1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL9658728 | 0.71 | POLB (0.37) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL9689432 | 0.70 | ALDH1A1 (0.36) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |