SCHEMBL9660835

SCHEMBL9660835

C[C@H]([C]=O)NC(=O)CNc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.47
LMNA P02545 4/20 0.46
ALDH1A1 P00352 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 1/20 0.46
ERCC1 P07992 3/20 0.44
ERCC4 Q92889 3/20 0.44
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GPR139 Q6DWJ6 1/20 0.40
ROCK2 O75116 1/20 0.40
GRK2 P25098 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9329532 1.00 PKM (0.47) PKMLMNAALDH1A1KMT2AMAPT
SCHEMBL24137901 0.83 LMNA (0.51) PKMLMNAALDH1A1KMT2AMAPT
SCHEMBL6623667 0.80 PKM (0.49) PKMLMNAALDH1A1KMT2AMAPT
SCHEMBL10425684 0.77 PKM (0.47) PKMLMNAALDH1A1KMT2AMAPT
SCHEMBL10333000 0.77 PKM (0.47) PKMLMNAALDH1A1KMT2AMAPT
SCHEMBL11403190 0.77 CTSC (0.50) PKMLMNAALDH1A1KMT2AMAPT
SCHEMBL27478057 0.77 POLB (0.59) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL10542964 0.77 POLB (0.59) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL8074262 0.75 MAPK1 (0.54) ALDH1A1
SCHEMBL8074253 0.75 MAPK1 (0.54) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234549-B1 METHOD FOR PRODUCTION OF CEPHALOSPORIN COMPOUNDS Takeda Chemical Industries, Ltd. (JP) 1992-12-16 EP disclosed
US-4980464-A Method for production of cephalosporin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-12-25 US disclosed
US-4822788-A MICROBIOCIDES, BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-18 US disclosed
US-4822790-A ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-18 US disclosed
US-4801703-A PHOSPHORUS COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-01-31 US disclosed
US-4782147-A ANTIBIOTIC TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-11-01 US disclosed
US-4771045-A 2-oxozetidinone derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-13 US disclosed
US-4725591-A USED WITH AMINO ACID DERIVATIVE ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-02-16 US disclosed
EP-0234549-A2 Method for production of cephalosporin compounds Takeda Chemical Industries, Ltd. (JP) 1987-09-02 EP disclosed
US-4684724-A ANTIBIOTICS, BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-08-04 US disclosed
EP-0095764-A2 2-Oxoazetidinone derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-12-07 EP disclosed
US-4416817-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1983-11-22 US disclosed
EP-0093376-A2 1-Sulfo-2-azetidinone derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-11-09 EP disclosed
EP-0083039-A1 4-Cyano-2-azetidinones and production thereof Takeda Chemical Industries, Ltd. (JP) 1983-07-06 EP disclosed
EP-0074611-A2 Method for production of cephalosporin compounds Takeda Chemical Industries, Ltd. (JP) 1983-03-23 EP disclosed
EP-0053815-A1 2-Oxoazetidine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-06-16 EP disclosed
EP-0053816-A1 1-Sulfo-2-oxoazetidine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-06-16 EP disclosed
EP-0053387-A1 Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor Takeda Chemical Industries, Ltd. (JP) 1982-06-09 EP disclosed
EP-0050965-A1 Beta-lactamase inhibitory composition Takeda Chemical Industries, Ltd. (JP) 1982-05-05 EP disclosed
EP-0021676-A1 3-Methoxy-2-oxoazetidine derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1981-01-07 EP disclosed