Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074262 | 1.00 | MAPK1 (0.54) | MAPK1NTSR1MMETP53FPR2 | |
| SCHEMBL4456109 | 0.84 | ERCC1 (0.50) | MMEALDH1A1 | |
| SCHEMBL4456099 | 0.84 | ERCC1 (0.50) | MMEALDH1A1 | |
| SCHEMBL13358894 | 0.81 | FNTA (0.51) | MMEACEALDH1A1 | |
| SCHEMBL13358896 | 0.81 | FNTA (0.51) | MMEACEALDH1A1 | |
| SCHEMBL6623667 | 0.81 | PKM (0.49) | MMELTA4HALDH1A1 | |
| SCHEMBL24137901 | 0.80 | LMNA (0.51) | ALDH1A1 | |
| SCHEMBL7365767 | 0.80 | MME (0.55) | MMEFPR2ACE | |
| SCHEMBL6670986 | 0.79 | GPR139 (0.63) | — | |
| SCHEMBL6670978 | 0.79 | GPR139 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038533-A1 | MEDICINAL COMPOSITIONS FOR TREATING IMMUNODEFICIENCY DISEASES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-09-27 | — | — | EP | disclosed |
| CN-1264308-A | Pharmaceutical composition for treating immunodeficiency diseases | NIPPON KAYAKU KK (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-0347820-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PREPARATION AND APPLICATION OF THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-04-21 | — | — | EP | disclosed |
| CN-1016341-B | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | MICROBIAL CHEMICAL RESEARCHING (JP) | 1992-04-22 | — | — | CN | disclosed |
| US-5061787-A | IMMUNOSUPPRESSANTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241797-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4956504-A | IMMUNOMODULATORS, ANTIBIOTICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0309971-A2 | New spergualin-related compound and pharmaceutical composition | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-04-05 | — | — | EP | disclosed |
| CN-87102538-A | New compound relevant and preparation method thereof with spergualin | — | 1987-11-18 | — | — | CN | disclosed |
| EP-0241797-A2 | Novel spergualin-related compounds and process for producing the same | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1987-10-21 | — | — | EP | disclosed |