Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660857 | 1.00 | NISCH (0.39) | NISCHSCN5ANOS3NOS1NOS2 | |
| SCHEMBL9690600 | 0.83 | MPI (0.43) | MAPTMEN1NPC1KMT2A | |
| SCHEMBL9690606 | 0.83 | MPI (0.43) | MAPTMEN1NPC1KMT2A | |
| SCHEMBL9660851 | 0.82 | SCN5A (0.38) | SCN5AMAPTNPC1TSHRKMT2A | |
| SCHEMBL9661581 | 0.80 | NPC1 (0.44) | NISCHMAPTMEN1NPC1KMT2A | |
| SCHEMBL9661588 | 0.80 | NPC1 (0.44) | NISCHMAPTMEN1NPC1KMT2A | |
| SCHEMBL28102967 | 0.77 | NOS3 (0.47) | NISCHSCN5ANOS3NOS1NOS2 | |
| SCHEMBL28102966 | 0.77 | NOS3 (0.47) | NISCHSCN5ANOS3NOS1NOS2 | |
| SCHEMBL9660828 | 0.77 | LMNA (0.36) | ALDH1A1 | |
| SCHEMBL9660834 | 0.77 | LMNA (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |