Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690600 | 1.00 | MPI (0.43) | MPIRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9660857 | 0.83 | NISCH (0.39) | MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9660852 | 0.83 | NISCH (0.39) | MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9690750 | 0.82 | MAPT (0.49) | RAB9ASMN1; SMN2MAPTMEN1LMNA | |
| SCHEMBL9690757 | 0.82 | MAPT (0.49) | RAB9ASMN1; SMN2MAPTMEN1LMNA | |
| SCHEMBL9690661 | 0.80 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL9690654 | 0.80 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL9688581 | 0.77 | KMT2A (0.45) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL9688567 | 0.77 | KMT2A (0.45) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL9690033 | 0.77 | SMN1; SMN2 (0.39) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |