Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660858 | 0.82 | ESR1 (0.52) | ESR1HTT | |
| SCHEMBL8492778 | 0.81 | GAA (0.43) | ESR1ALDH1A1GAAPKMKMT2A | |
| SCHEMBL9659593 | 0.81 | ESR1 (0.61) | ESR1TSHRHTT | |
| SCHEMBL9661727 | 0.80 | ESR1 (0.61) | ESR1 | |
| SCHEMBL8490520 | 0.79 | TSHR (0.58) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL9661501 | 0.78 | FFAR4 (0.52) | ESR1KDM4EMAPT | |
| SCHEMBL69907 | 0.78 | GAA (0.58) | ESR1ALDH1A1GAAPKMPOLB | |
| SCHEMBL29599083 | 0.78 | GAA (0.58) | ESR1ALDH1A1GAAPKMPOLB | |
| SCHEMBL9661792 | 0.76 | FFAR4 (0.55) | — | |
| SCHEMBL12084146 | 0.73 | ALDH1A1 (0.67) | ESR1ALDH1A1GAAPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466096-A1 | Derivatives of 4-hydroxyphenylsulfone | JUJO PAPER CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |