SCHEMBL9660858

SCHEMBL9660858

CCCOc1ccc(S(=O)(=O)c2ccc(O)c(C)c2)cc1C

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 16/20 0.52
WDR5 P61964 3/20 0.46
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9659593 0.93 ESR1 (0.61) ESR1WDR5HTT
SCHEMBL9661727 0.92 ESR1 (0.61) ESR1WDR5
SCHEMBL9661872 0.89 WDR5 (0.46) ESR1WDR5HTT
SCHEMBL7179931 0.86 CA12 (0.56) ESR1HTT
SCHEMBL9661628 0.83 KMT2A (0.51) WDR5HTT
SCHEMBL9660875 0.82 ESR1 (0.44) ESR1HTT
SCHEMBL9660854 0.81 ALDH1A1 (0.47) ESR1WDR5HTT
SCHEMBL8490520 0.80 TSHR (0.58) HTT
SCHEMBL5499410 0.80 HTT (0.46) WDR5HTT
SCHEMBL9661501 0.80 FFAR4 (0.52) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466096-A1 Derivatives of 4-hydroxyphenylsulfone JUJO PAPER CO., LTD. (JP) 1992-01-15 EP disclosed