Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.61 |
| ▸ | WDR5 | P61964 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661727 | 0.96 | ESR1 (0.61) | ESR1WDR5S1PR3 | |
| SCHEMBL9660858 | 0.93 | ESR1 (0.52) | ESR1WDR5HTT | |
| SCHEMBL4535344 | 0.82 | S1PR3 (0.60) | ESR1WDR5CA12CA1CA2 | |
| SCHEMBL7179931 | 0.82 | CA12 (0.56) | ESR1CA12CA1CA2TSHR | |
| SCHEMBL9661872 | 0.82 | WDR5 (0.46) | ESR1WDR5HTT | |
| SCHEMBL9660875 | 0.81 | ESR1 (0.44) | ESR1TSHRHTT | |
| SCHEMBL8490520 | 0.79 | TSHR (0.58) | TSHRHTT | |
| SCHEMBL5499410 | 0.79 | HTT (0.46) | WDR5TSHRHTT | |
| SCHEMBL9661501 | 0.78 | FFAR4 (0.52) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL9662284 | 0.78 | CA12 (0.54) | ESR1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466096-A1 | Derivatives of 4-hydroxyphenylsulfone | JUJO PAPER CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |