Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210532 | 0.82 | KDM4E (0.36) | KDM4EABCB1MALT1ABCC9KCNE1 | |
| SCHEMBL9662677 | 0.80 | ABCC9 (0.36) | KDM4EABCB1MALT1ABCC9KCNE1 | |
| SCHEMBL9370492 | 0.77 | KDM4E (0.36) | KDM4EABCB1MALT1ABCC9KCNE1 | |
| SCHEMBL8795220 | 0.76 | ABCC9 (0.34) | KDM4EABCB1MALT1ABCC9KCNE1 | |
| SCHEMBL8795668 | 0.76 | ABCC9 (0.34) | KDM4EABCB1MALT1ABCC9KCNE1 | |
| SCHEMBL10381355 | 0.74 | ABCB1 (0.35) | KDM4EABCB1ABCC9 | |
| SCHEMBL7693373 | 0.73 | KDM4E (0.38) | KDM4E | |
| SCHEMBL10990741 | 0.73 | ABCC9 (0.48) | ABCB1MALT1ABCC9CYP1A2CYP3A4 | |
| SCHEMBL5852754 | 0.73 | MALT1 (0.39) | KDM4EABCB1MALT1ABCC9KCNE1 | |
| SCHEMBL9354700 | 0.73 | MAPT (0.33) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488301-A1 | New benzopyran compounds with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-03 | — | — | EP | disclosed |