Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 2/20 | 0.31 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925383 | 0.81 | BRD4 (0.35) | BRD4ALDH1A1ALPLPLAAALPG | |
| SCHEMBL13694927 | 0.79 | ALPL (0.34) | BRD4ALDH1A1ALPLPLAAALPG | |
| SCHEMBL13512616 | 0.75 | AURKA (0.40) | ADORA1ADORA2ABRD4ADORA2B | |
| SCHEMBL12401883 | 0.71 | TLR8 (0.52) | ADORA1ADORA2ABRD4ADORA3ALDH1A1 | |
| SCHEMBL15573640 | 0.71 | — | — | |
| SCHEMBL23213724 | 0.65 | ALPL (0.32) | ALDH1A1ALPLPLAAALPG | |
| SCHEMBL19924655 | 0.65 | BRD4 (0.69) | BRD4 | |
| SCHEMBL11718699 | 0.64 | EP300 (0.43) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL5201162 | 0.64 | CDK1 (0.35) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL8178792 | 0.64 | CNR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262096-B1 | AMINOPYRAZINONES AND AMINOTRIAZINONES | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |
| US-4920223-A | Herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | disclosed |
| US-4871853-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| US-4795486-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION, 444 SAW MILL RIVER ROAD, ARDSLEY, NEW YORK 10502 A NY CORP. | 1989-01-03 | — | — | US | disclosed |
| EP-0262096-A1 | Aminopyrazinones and aminotriazinones | CIBA-GEIGY AG (CH) | 1988-03-30 | — | — | EP | disclosed |