Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455909 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL18484513 | 0.77 | GABRA1 (0.50) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL8091206 | 0.77 | POLB (0.49) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL10367993 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL9664110 | 0.76 | MAPK1 (0.44) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL29384783 | 0.74 | TSHR (0.65) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL322161 | 0.74 | TSHR (0.65) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL13689698 | 0.74 | MEN1 (0.59) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL8492279 | 0.74 | ERCC5 (0.67) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 | |
| SCHEMBL992504 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TSHRCASP1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254086-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-08 | — | — | EP | disclosed |
| EP-0243983-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-04 | — | — | EP | disclosed |
| EP-0121979-B1 | AZOLYLMETHYL TETRAHYDROFURAN DERIVATIVES AS PLANT GROWTH REGULATORS AND FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-09-26 | — | — | EP | disclosed |
| EP-0256266-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-24 | — | — | EP | disclosed |
| EP-0254086-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |
| EP-0243983-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4636247-A | TETRAHYDROFURANYLMETHYLIMIDAZOLES AND -TRIAZOLES, FUNGICIDES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-13 | — | — | US | disclosed |
| EP-0121979-A2 | Azolylmethyl tetrahydrofuran derivatives as plant growth regulators and fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-17 | — | — | EP | disclosed |