Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455909 | 0.82 | ALDH1A1 (0.50) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL18484513 | 0.81 | GABRA1 (0.50) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL20156555 | 0.81 | FLT1 (0.48) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL992504 | 0.80 | ALDH1A1 (0.48) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL432702 | 0.78 | MEN1 (0.55) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL14404139 | 0.77 | NOS2 (0.46) | TDP1RECQLALDH1A1KMT2AMAPK1 | |
| SCHEMBL13689698 | 0.77 | MEN1 (0.59) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL20683682 | 0.77 | RAB9A (0.41) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9664124 | 0.77 | ALDH1A1 (0.50) | POLBTDP1THRBRECQLL3MBTL1 | |
| SCHEMBL29712843 | 0.76 | ALDH1A1 (0.69) | POLBTDP1THRBRECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053218-A1 | DIOL COMPOUNDS AS INTERMEDIATES FOR PREPARING ANTIMYCOTIC COMPOUNDS | ZAMBON GROUP S.p.A. (IT) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999029645-A1 | DIOL COMPOUNDS AS INTERMEDIATES FOR PREPARING ANTIMYCOTIC COMPOUNDS | ZAMBON GROUP S.P.A. (IT) | 1999-06-17 | — | — | WO | disclosed |