Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543440 | 0.91 | ALDH1A1 (0.36) | CFTR | |
| SCHEMBL9664094 | 0.90 | POLB (0.32) | — | |
| SCHEMBL8547860 | 0.88 | — | — | |
| SCHEMBL9663223 | 0.88 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL7308635 | 0.84 | — | — | |
| SCHEMBL8547883 | 0.83 | PPARG (0.32) | AGTR1AGTR2 | |
| SCHEMBL9429570 | 0.82 | ALDH1A1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7310871 | 0.82 | AGTR2 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8547600 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL8544240 | 0.80 | AGTR1 (0.30) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514198-A1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |