Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798676 | 0.86 | NFE2L2 (0.52) | ALDH1A1MAPTNPC1TSHRNFE2L2 | |
| SCHEMBL1202896 | 0.86 | HSD17B10 (0.58) | ALDH1A1MAPTNPC1HSD17B10LMNA | |
| SCHEMBL7024646 | 0.83 | — | — | |
| SCHEMBL5776485 | 0.83 | — | — | |
| SCHEMBL35226 | 0.83 | — | — | |
| Fluoride SCHEMBL21986315 | 0.80 | LMNA (0.57) | ALDH1A1MAPTNPC1HTTHSD17B10 | |
| SCHEMBL3821175 | 0.80 | — | — | |
| SCHEMBL2972168 | 0.80 | — | — | |
| SCHEMBL18240610 | 0.78 | NFE2L2 (0.54) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18240678 | 0.78 | CHRM5 (0.48) | ALDH1A1MAPTNPC1NFE2L2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |
| US-5156669-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| EP-0222322-B1 | CEPHALOSPORIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0222322-A2 | Cephalosporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-20 | — | — | EP | disclosed |