Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31256698 | 0.89 | MAPK1 (0.47) | HPGDMAPTRAB9AL3MBTL1GAA | |
| SCHEMBL17907419 | 0.82 | ALDH1A1 (0.38) | HPGDMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL203697 | 0.82 | HPGD (1.00) | HPGDMAPTRAB9AESRRAL3MBTL1 | |
| SCHEMBL3301210 | 0.82 | HPGD (1.00) | HPGDMAPTRAB9AESRRAL3MBTL1 | |
| SCHEMBL11233742 | 0.78 | KMT2A (0.54) | HPGDMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9789228 | 0.77 | MAPT (0.86) | HPGDMAPTRAB9AESRRAL3MBTL1 | |
| SCHEMBL9999838 | 0.75 | MAPT (0.83) | HPGDMAPTRAB9AESRRAL3MBTL1 | |
| SCHEMBL903435 | 0.75 | MAPT (0.83) | HPGDMAPTRAB9AESRRAL3MBTL1 | |
| SCHEMBL20710436 | 0.75 | LTA4H (0.52) | SMN1; SMN2TSHRHTTLMNAMMP13 | |
| SCHEMBL16841481 | 0.75 | TEAD4 (0.50) | HPGDMAPTRAB9AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324472-B1 | KETENEDITHIOACETAL DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME AS WELL AS A COMPOSITION CONTAINING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5098928-A | Antilipemic agents and treatment of arteriosclerosis | NIHON NOHYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0324472-A2 | Ketenedithioacetal derivatives and processes for producing the same as well as a composition containing the same | NIHON NOHYAKU CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |